Mechanism of Semaglutide Pills and its Comparison with Injectable form

Posted On November 13, 2023December 5, 2023

Posted By Steffy Alen

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Action:

Semaglutide Pills reduces glucose levels in your blood, by increasing insulin production in your body. It also reduces the amount of new glucose released into the blood and slows down your digestion.

Mechanism:

Semaglutide makes the body use a hormone called Glucagon like peptide-1 (GLP-1) better by turning on its receptors. It helps to lower blood sugar in different ways, such as making more insulin (only when the blood sugar is high), stopping a hormone called glucagon that raises blood sugar, and slowing down the liver from making sugar. This helps to keep the blood sugar normal both before and after eating. It also binds with high affinity with plasma albumin which means it increases the level of drug stability.

Advantages:

Semaglutide pills can help you lose weight by making you feel full and eat less. They mock the natural hormones that control your hunger and slows the speed of your digestion. This may lead to a sensation of fullness. This medication also lowers the risk of heart disease and the rate of death in diabetic patients. It is useful for managing atherosclerotic diseases, such as heart or blood vessel diseases, and may reduce the risk of stroke by affecting blood pressure levels. By playing role in weight management it may also reduce the risk of obesity related diseases.

Comparison of Semaglutide Pills and Injectable Semaglutides:

Patients who are prescribed semaglutides have an option of either ingesting semaglutides orally or injecting it subcutaneously. By both routes semaglutides are effective. Oral semaglutides used in high dosage as compared to injectable semaglutides. The dosage of oral semaglutide is 3mg, 7mg and 14mg which should be used daily and injectable semaglutide is used 0.5 to 2 mg per week. Semaglutide pills have to be taken daily. Semaglutide Pills is a great option for those patients who feel reserved with injectable medications.

Potential Side Effects:

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Although side effects associated with semaglutides are uncommon. Most of the associated side effects are

Nausea
Vomiting
Stomach Pain
Fatigue
Low Blood Sugar
Pancreatitis
Gall Bladder Disease
Kidney Damage
Allergic Reactions
Thyroid Tumors
Dysuria
Polyuria
Dizziness
Blurred Vision

If these symptoms persist refer to your doctor.

Precautions:

Semaglutide pills may trigger an allergic reaction, notify your doctor. Also talk to your doctor if you are using any other medication like blood pressure regulating medicine or any steroids. These type of medicines may interact with semaglutides and may cause reactions. Patients with conditions like diabetic retinopathy, kidney disorders, gastroparesis, pancreatitis, intestinal disorders, or gall bladder disease may require special care. While semaglutide is not sedative but strenuous exercise combined with this medication can lead to excessively low blood sugar due to sweating, resulting in drowsiness, dizziness, and lethargy. Therefore, activities require full attention, like driving, should be avoided. Consuming alcohol while using this medication carries the risk of lowering blood sugar levels below normal.

For those having a plan to get pregnant, already pregnant, or suspecting pregnancy, consulting a doctor is necessary, as there may be potential risks related to pregnancy. Consultation with a doctor should occur two months before attempting pregnancy because medication adjustments may be needed.

Breastfeeding mothers should also consult with their doctors regarding the use of this medication.

Contraindications:

Semaglutide pills are not prescribed for individuals with a personal or family history of thyroid tumors, specifically thyroid C cell tumors or medullary thyroid carcinoma (MTC). It is also contraindicated in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2).

How to use this medication:

The best time to take semaglutide pill is 30 minutes before meal. Use only plain water to take this medicine. Avoid any beverage or drink to ingest medicine. Do not eat any meal or vitamins for at least 30 minutes after taking semaglutide pills. The Dosage of medicine is increased after every 30 days.